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Fine-needle aspiration cytology of benign and malignant adenomyoepithelioma: report of two cases.
- Source :
-
Diagnostic cytopathology [Diagn Cytopathol] 2002 Jan; Vol. 26 (1), pp. 29-34. - Publication Year :
- 2002
-
Abstract
- Cytological features of a malignant spindle-cell variant and a benign tubular variant of adenomyoepithelioma were examined to improve diagnosis of this tumor. Fine-needle aspiration cytology, of both a malignant and a benign case, characterized cellular and cohesive cell clusters composed of epithelial and myoepithelial cells. The smears of the malignant case were rich in spindle-shaped myoepithelial cells, admixed with a few epithelial cells. In about a fourth of the clusters, atypical cells with enlarged hyperchromatic nuclei and prominent nucleoli comprised more than 20% of cells. The smears of the benign case were composed of tubular epithelial cells surrounding one to several layers of myoepithelial cells with clear cytoplasm. Mild atypia was occasionally noticed. A review of the literature showed that a cytological diagnosis of malignancy is not warranted, if nuclear atypia is not generally severe. Focal severe atypia is not definitively indicative of benignity or malignancy.<br /> (Copyright 2002 Wiley-Liss, Inc.)
- Subjects :
- Actins analysis
Aged
Biomarkers, Tumor analysis
Biopsy, Needle
Breast Neoplasms chemistry
Breast Neoplasms surgery
Carcinoma, Adenoid Cystic chemistry
Carcinoma, Adenoid Cystic surgery
Cell Nucleus pathology
Female
Humans
Immunoenzyme Techniques
Keratins analysis
Neoplasm Proteins analysis
Neoplasms, Second Primary
Breast Neoplasms pathology
Carcinoma, Adenoid Cystic pathology
Subjects
Details
- Language :
- English
- ISSN :
- 8755-1039
- Volume :
- 26
- Issue :
- 1
- Database :
- MEDLINE
- Journal :
- Diagnostic cytopathology
- Publication Type :
- Academic Journal
- Accession number :
- 11782084
- Full Text :
- https://doi.org/10.1002/dc.10037