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Influence of hyperbranched multi-methacrylates for dental neat resins on proliferation of human gingival fibroblasts.
- Source :
-
Biomacromolecules [Biomacromolecules] 2001 Spring; Vol. 2 (1), pp. 217-22. - Publication Year :
- 2001
-
Abstract
- We have previously shown that hyperbranched multi-methacrylate (H-MMA)-modified dental resins have VLC activities, lower polymerization shrinkage, and improved mechanical properties, compared to the 2,2-bis[4-(2-hydroxy-3-methacryloyolxypropoxy)phenyl]propane/triethyleneglycol dimethacrylate (BisGMA/TEGDMA) neat resin. The results are due to the unique molecular structure and high molecular weight of H-MMA intermediates. The purpose of this study was to evaluate the biocompatibility of H-MMA-modified dental neat resins. The cell proliferation of three human gingival fibroblast strains on either H-MMA, BisGMA/TEGDMA, or a polystyrene disk was examined. Following 10 days of cell proliferation, there was no statistical difference in cell number between H-MMA-modified and unmodified resin disks. H-MMA-modified resins had less free monomer leaching than the unmodified resin but showed similar properties in water sorption and contact angle values. All these results suggest that the biocompatibility of H-MMA-modified dental neat resins is as good as that of commercially used BisGMA/TEGDMA resin and H-MMA has potential applications in dental composites.
- Subjects :
- Adult
Aged
Biocompatible Materials adverse effects
Biocompatible Materials chemistry
Cell Division drug effects
Cells, Cultured
Female
Fibroblasts cytology
Humans
Male
Molecular Structure
Molecular Weight
Water
Dental Materials adverse effects
Dental Materials chemistry
Fibroblasts drug effects
Gingiva cytology
Methacrylates adverse effects
Methacrylates chemistry
Resins, Synthetic adverse effects
Resins, Synthetic chemistry
Subjects
Details
- Language :
- English
- ISSN :
- 1525-7797
- Volume :
- 2
- Issue :
- 1
- Database :
- MEDLINE
- Journal :
- Biomacromolecules
- Publication Type :
- Academic Journal
- Accession number :
- 11749176
- Full Text :
- https://doi.org/10.1021/bm000101p