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Infection of the subcutis and skin of cats with rapidly growing mycobacteria: a review of microbiological and clinical findings.
- Source :
-
Journal of feline medicine and surgery [J Feline Med Surg] 2000 Mar; Vol. 2 (1), pp. 35-48. - Publication Year :
- 2000
-
Abstract
- Mycobacteria were isolated and characterised from 49 cats with extensive infections of the subcutis and skin. Cats were generally between 3 and 10 years of age, and female cats were markedly over-represented. All isolates were rapid-growers and identified as either Mycobacteria smegmatis (40 strains) or M fortuitum (nine strains). On the basis of Etest for minimum inhibitory concentration and/or disc diffusion susceptibility testing, all strains of M smegmatis were susceptible to trimethoprim while all strains of M fortuitum were resistant. M smegmatis strains were typically susceptible to doxycycline, gentamicin and fluoroquinolones but not clarithromycin. All M fortuitum strains were susceptible to fluoroquinolones, and often also susceptible to gentamicin, doxycycline and clarithromycin. Generally, M smegmatis strains were more susceptible to antimicrobial agents than M fortuitum strains. Treatment of mycobacterial panniculitis involves long courses of antimicrobial agents, typically of 3-6 months, chosen on the basis of in vitro susceptibility testing and often combined with extensive surgical debridement and wound reconstruction. These therapies will result in effective cure of the disease. One or a combination of doxycycline, ciprofloxacin/enrofloxacin or clarithromycin are the drugs of choice for long-term oral therapy.<br /> (Copyright 2000 European Society of Feline Medicine.)
- Subjects :
- Animals
Anti-Bacterial Agents pharmacology
Anti-Bacterial Agents therapeutic use
Cat Diseases drug therapy
Cats
Drug Resistance, Bacterial
Drug Resistance, Multiple, Bacterial
Female
Male
Microbial Sensitivity Tests
Mycobacterium Infections, Nontuberculous drug therapy
Mycobacterium Infections, Nontuberculous microbiology
Mycobacterium fortuitum drug effects
Mycobacterium smegmatis drug effects
Panniculitis drug therapy
Panniculitis microbiology
Panniculitis veterinary
Sex Distribution
Skin Diseases, Bacterial drug therapy
Cat Diseases microbiology
Mycobacterium Infections, Nontuberculous veterinary
Mycobacterium fortuitum growth & development
Mycobacterium smegmatis growth & development
Skin Diseases, Bacterial veterinary
Subjects
Details
- Language :
- English
- ISSN :
- 1098-612X
- Volume :
- 2
- Issue :
- 1
- Database :
- MEDLINE
- Journal :
- Journal of feline medicine and surgery
- Publication Type :
- Academic Journal
- Accession number :
- 11716590
- Full Text :
- https://doi.org/10.1053/jfms.2000.0051