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Antimicrobial activity of Mallotus oppositifolium extractives.
- Source :
-
African journal of medicine and medical sciences [Afr J Med Med Sci] 2000 Sep-Dec; Vol. 29 (3-4), pp. 281-3. - Publication Year :
- 2000
-
Abstract
- A bioactivity monitored phytochemical examination of the morphological parts of Mallotus oppositifolium utilizing the hole-in-plate bioassay procedure against gram-positive, gram-negative bacteria and fungal isolates resulted in the location of significant antimicrobial activity in the acidic fraction (HAF) of the hexane extract of the powdered leaves. Minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) values were 32.5 microg/ml and 65 microg/ml against Pseudomonas aeruginosa NCTC 6750 and 25 microg/ml and 50 microg/ml against Staphylococcus aureus NCTC 6571 respectively. These activities were found comparable with standard drugs.
- Subjects :
- Biological Assay
Chemical Fractionation methods
Chromatography, Thin Layer
Drug Evaluation, Preclinical
Humans
Microbial Sensitivity Tests
Nigeria
Plant Extracts chemistry
Fungi drug effects
Gram-Negative Bacteria drug effects
Gram-Positive Bacteria drug effects
Medicine, African Traditional
Plants, Medicinal chemistry
Plants, Medicinal physiology
Subjects
Details
- Language :
- English
- ISSN :
- 0309-3913
- Volume :
- 29
- Issue :
- 3-4
- Database :
- MEDLINE
- Journal :
- African journal of medicine and medical sciences
- Publication Type :
- Academic Journal
- Accession number :
- 11714006