Inhibition of drug-sensitive and drug-resistant strains of Mycobacterium tuberculosis by diospyrin, isolated from Euclea natalensis.

Authors :: Lall N
Meyer JJ
Source :: Journal of ethnopharmacology [J Ethnopharmacol] 2001 Dec; Vol. 78 (2-3), pp. 213-6.
Publication Year :: 2001
Abstract: The binaphthoquinoid, diospyrin, was isolated from Euclea natalensis A.DC., and evaluated for its activity against drug-sensitive and drug-resistant strains of Mycobacterium tuberculosis. The minimal inhibitory concentration (MIC) of diospyrin was found to be 100 microg/ml for all the M. tuberculosis strains.

Subjects :: Drug Resistance, Multiple
Microbial Sensitivity Tests
Naphthoquinones isolation & purification
Mycobacterium tuberculosis drug effects
Naphthoquinones pharmacology
Plant Extracts pharmacology

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