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Good metabolic control is associated with better quality of life in 2,101 adolescents with type 1 diabetes.
- Source :
-
Diabetes care [Diabetes Care] 2001 Nov; Vol. 24 (11), pp. 1923-8. - Publication Year :
- 2001
-
Abstract
- Objective: It is unclear whether the demands of good metabolic control or the consequences of poor control have a greater influence on quality of life (QOL) for adolescents with diabetes. This study aimed to assess these relations in a large international cohort of adolescents with diabetes and their families.<br />Research Design and Methods: The study involved 2,101 adolescents, aged 10-18 years, from 21 centers in 17 countries in Europe, Japan, and North America. Clinical and demographic data were collected from March through August 1998. HbA(1c) was analyzed centrally (normal range 4.4-6.3%; mean 5.4%). Adolescent QOL was assessed by a previously developed Diabetes Quality of Life (DQOL) questionnaire for adolescents, measuring the impact of diabetes, worries about diabetes, satisfaction with life, and health perception. Parents and health professionals assessed family burden using newly constructed questionnaires.<br />Results: Mean HbA(1c) was 8.7% (range 4.8-17.4). Lower HbA(1c) was associated with lower impact (P < 0.0001), fewer worries (P < 0.05), greater satisfaction (P < 0.0001), and better health perception (P < 0.0001) for adolescents. Girls showed increased worries (P < 0.01), less satisfaction, and poorer health perception (P < 0.01) earlier than boys. Parent and health professional perceptions of burden decreased with age of adolescent (P < 0.0001). Patients from ethnic minorities had poorer scores for impact (P < 0.0001), worries (P < 0.05), and health perception (P < 0.01). There was no correlation between adolescent and parent or between adolescent and professional scores.<br />Conclusions: In a multiple regression model, lower HbA(1c) was significantly associated with better adolescent-rated QOL on all four subscales and with lower perceived family burden as assessed by parents and health professionals.
- Subjects :
- Adolescent
Biomarkers
Child
Cross-Cultural Comparison
Diabetes Mellitus, Type 1 blood
Europe
Female
Health Status
Humans
Japan
Male
Normal Distribution
North America
Reference Values
Regression Analysis
Sex Factors
Surveys and Questionnaires
Blood Glucose metabolism
Diabetes Mellitus, Type 1 physiopathology
Diabetes Mellitus, Type 1 psychology
Glycated Hemoglobin metabolism
Quality of Life
Subjects
Details
- Language :
- English
- ISSN :
- 0149-5992
- Volume :
- 24
- Issue :
- 11
- Database :
- MEDLINE
- Journal :
- Diabetes care
- Publication Type :
- Academic Journal
- Accession number :
- 11679458
- Full Text :
- https://doi.org/10.2337/diacare.24.11.1923