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[Correction of coronary insufficiency by dihydropiridine antagonists of calcium in patients with coronary artery bypass].

Authors :
Tepliakov AT
Rybal'chenko EV
Garganeeva AA
Chernov VI
Source :
Terapevticheskii arkhiv [Ter Arkh] 2001; Vol. 73 (8), pp. 56-9.
Publication Year :
2001

Abstract

Aim: To study antiischemic and antianginal efficiency of adalat and its prolonged form adalat SL, dihydropiridin antagonists of calcium, in patients 1-3 years after surgical correction of stenosing coronary atherosclerosis.<br />Material and Methods: The drugs were tried in 40 patients with angina of effort (functional class II-III) with a satisfactory inotropic function of the left ventricle 1 to 3 years after coronary artery bypass surgery (CABS). Myocardial circulation was measured with one-photon emission computed tomography using 99m-Tc-MIBI (CT).<br />Results: A 3-week therapy with adalat reduced the number of anginal attacks, nitroglycerin requirement, enhanced exercise tolerance. CT showed that myocardial blood flow significantly improved.<br />Conclusion: Adalat proved to be effective in patients after CABS. Its prolonged form adalat SL is preferable.

Details

Language :
Russian
ISSN :
0040-3660
Volume :
73
Issue :
8
Database :
MEDLINE
Journal :
Terapevticheskii arkhiv
Publication Type :
Academic Journal
Accession number :
11599269