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[Pelvic type of chronic recurrent multifocal osteomyelitis].
- Source :
-
Klinische Padiatrie [Klin Padiatr] 2001 Sep-Oct; Vol. 213 (5), pp. 277-84. - Publication Year :
- 2001
-
Abstract
- We report about the juvenile and adolescent pelvic type of CRMO in 7 girls and 4 boys. The results show from solitary up to 7 pelvic lesions (average 3 lesions) predominantly in the acetabular and paraacetabular region (sometimes with hip joint effusion as a sign for concomitant coxitis).Tc99m-bone-scan is helpful to evaluate exactly the pattern of bone affection. We find 3 stages of an primarily chronic, non-purulent osteomyelitis going along with a "plasma-cell-sclerotic process", leading to a Garrè-type sclerosing end-stage, which probably heals after some years spontaneously, projecting on clinical symptoms and radiological appearance. The concomitant coxitis ("sympathetic coxitis") is clinically often in the foreground, but reversible. Pain in case of CRMO responds surprisingly well on medication with acithromycine. Knowing about CRMO in its different clinical appearances - especially concerning what we call "sympathetic coxitis" - can be a useful for pediatric rheumatologists and orthopedic surgeons, as well as MRI-focused radiologists and pathologists. Therapy might find a useful drug in acithromycine. In conclusion we d like to point out, that CRMO is one entity under the "roof" of the so called SAPHO-syndrome, which again shows us, that SAPHO-syndrome ist not a diagnosis itself but more a sign-post on the way to a correct diagnosis.
- Subjects :
- Acquired Hyperostosis Syndrome diagnosis
Adolescent
Adult
Age Factors
Anti-Bacterial Agents administration & dosage
Anti-Bacterial Agents therapeutic use
Azithromycin administration & dosage
Azithromycin therapeutic use
Child
Child, Preschool
Chronic Disease
Diagnosis, Differential
Female
Humans
Male
Recurrence
Time Factors
Osteomyelitis diagnosis
Osteomyelitis drug therapy
Osteomyelitis pathology
Pelvic Bones pathology
Subjects
Details
- Language :
- German
- ISSN :
- 0300-8630
- Volume :
- 213
- Issue :
- 5
- Database :
- MEDLINE
- Journal :
- Klinische Padiatrie
- Publication Type :
- Academic Journal
- Accession number :
- 11582526
- Full Text :
- https://doi.org/10.1055/s-2001-17219