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Changes in the rate of genotypic resistance to antiretroviral drugs in Spain.
- Source :
-
AIDS (London, England) [AIDS] 2001 Sep 28; Vol. 15 (14), pp. 1894-6. - Publication Year :
- 2001
-
Abstract
- Genotypic resistance to antiretroviral drugs was examined in 684 individuals attending 18 outpatient clinics distributed across Spain in June 2000. Compared with similar surveys conducted before 1998, the prevalence of resistance to nucleosides has declined significantly among naive chronic HIV carriers. In contrast, resistance among pre-treated patients has increased; resistance to all three drug families having been recognized in nearly a quarter of patients.
- Subjects :
- Anti-HIV Agents therapeutic use
Drug Resistance, Multiple, Viral genetics
Genotype
HIV Infections drug therapy
HIV Infections epidemiology
HIV Protease genetics
HIV Protease Inhibitors therapeutic use
HIV Reverse Transcriptase genetics
HIV-1 enzymology
HIV-1 genetics
Humans
Mutation
Reverse Transcriptase Inhibitors therapeutic use
Spain epidemiology
Anti-HIV Agents pharmacology
Drug Resistance, Viral genetics
HIV Infections virology
HIV Protease Inhibitors pharmacology
HIV-1 drug effects
Reverse Transcriptase Inhibitors pharmacology
Subjects
Details
- Language :
- English
- ISSN :
- 0269-9370
- Volume :
- 15
- Issue :
- 14
- Database :
- MEDLINE
- Journal :
- AIDS (London, England)
- Publication Type :
- Academic Journal
- Accession number :
- 11579258
- Full Text :
- https://doi.org/10.1097/00002030-200109280-00025