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Genetic subtypes of HIV type 1 viruses circulating in the Czech Republic.
- Source :
-
AIDS research and human retroviruses [AIDS Res Hum Retroviruses] 2001 Sep 01; Vol. 17 (13), pp. 1305-10. - Publication Year :
- 2001
-
Abstract
- We analyzed the genetic diversity of HIV-1 strains circulating in the Czech Republic. Phylogenetic analysis of the env and gag gene sequence fragments from 39 isolates revealed that the majority of these strains (32 of 39, 82%) were of subtype B; other genetic subtypes identified were A, C, F, and recombinant circulating form CRF01_AE. The isolates that did not cluster with subtype B originated almost exclusively from a heterosexual route of transmission. The molecular epidemiological data are suggestive of multiple entry of HIV-1 infection into the Czech Republic and show that the genetic pattern of the HIV-1 strains circulating in this country corresponds to that found in other European countries.
- Subjects :
- Amino Acid Sequence
Czech Republic epidemiology
Evolution, Molecular
Female
Genes, env genetics
Genes, gag genetics
Genetic Variation genetics
Genotype
HIV Envelope Protein gp120 chemistry
HIV Envelope Protein gp120 genetics
HIV Infections epidemiology
HIV-1 isolation & purification
Humans
Male
Molecular Sequence Data
Phylogeny
HIV Infections virology
HIV-1 classification
HIV-1 genetics
Subjects
Details
- Language :
- English
- ISSN :
- 0889-2229
- Volume :
- 17
- Issue :
- 13
- Database :
- MEDLINE
- Journal :
- AIDS research and human retroviruses
- Publication Type :
- Academic Journal
- Accession number :
- 11559432
- Full Text :
- https://doi.org/10.1089/088922201750461384