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Detection of restenosis after percutaneous transluminal coronary angioplasty using the exercise treadmill test and technetium 99m-sestamibi scintigraphy.
- Source :
-
Journal of the Medical Association of Thailand = Chotmaihet thangphaet [J Med Assoc Thai] 2001 Mar; Vol. 84 (3), pp. 307-13. - Publication Year :
- 2001
-
Abstract
- Background: The detection of myocardial ischemia after percutaneous transluminal coronary angioplasty (PTCA) is important because 30-50 per cent of the patients will develop restenosis within 6 months. Symptoms of chest pain and exercise stress test (EST) have shown to be less sensitive for detection of ischemia than exercise Technetium-99m Sestamibi (Tc-99m MIBI). The purpose of this study was to compare the sensitivity and specificity of chest pain, EST and Tc-99m MIBI with coronary angiography (CAG).<br />Method: Tc-99m MIBI with SPECT imaging was performed at months 1, 3 and 6 and CAG was repeated 6 months after successful PTCA. Earlier Tc-99m MIBI and CAG were performed in patients with recurrent angina pectoris or suspected restenosis.<br />Results: Forty six patients (M 29, F 17) who had undergone successful angioplasty were prospectively enrolled. Their mean age was 61 +/- 19 yrs. Eighty eight lesions (LAD63%, LCX34%, RCA19%) were performed. Lesion characteristics were type A in 9 per cent, type in B 30 per cent and type C in 61 per cent. Fifty four per cent of PTCA were performed for single vessel disease and 46 per cent for multivessel disease. The mean duration of time between PTCA and follow-up CAG was 6.1 +/- 2.7 months. We detected restenosis from CAG in 58 per cent of the cases. The Tc-99m MIBI had higher sensitivity to detect restenosis than anginal pain (85.0% vs 39.4% p < 0.005) or EST (85.0% vs 63.6% p < 0.05) when compared with CAG. The overall accuracy of Tc-99m MIBI for the detection of restenosis was 80 per cent.<br />Conclusion: Tc-99m MIBI with SPECT imaging constitutes a better means than symptoms or exercise test to detect restenosis after successful coronary angioplasty.
- Subjects :
- Adult
Aged
Coronary Disease diagnostic imaging
Coronary Disease therapy
Exercise Test
Female
Humans
Male
Middle Aged
Prospective Studies
Sensitivity and Specificity
Angioplasty, Balloon, Coronary
Coronary Disease diagnosis
Radiopharmaceuticals
Technetium Tc 99m Sestamibi therapeutic use
Tomography, Emission-Computed, Single-Photon
Subjects
Details
- Language :
- English
- ISSN :
- 0125-2208
- Volume :
- 84
- Issue :
- 3
- Database :
- MEDLINE
- Journal :
- Journal of the Medical Association of Thailand = Chotmaihet thangphaet
- Publication Type :
- Academic Journal
- Accession number :
- 11460930