Back to Search
Start Over
The body weight-walking distance product as related to lung function, anaerobic threshold and peak VO2 in COPD patients.
The body weight-walking distance product as related to lung function, anaerobic threshold and peak VO2 in COPD patients.
- Source :
-
Respiratory medicine [Respir Med] 2001 Jul; Vol. 95 (7), pp. 618-26. - Publication Year :
- 2001
-
Abstract
- The product of walking distance and body weight (D x W) mimics the work of walking. We hypothesized the superiority of D x W to walking distance (D) alone in any correlation with lung function, anaerobic threshold (AT) and maximal oxygen uptake (VO2max). We further hypothesized that the D x W product for a 6-min walk test (6 MWT) would correlate with the AT and VO2max because all three are markers of exercise ability. Thirty-three male chronic obstructive pulmonary disease (COPD) patients with mean forced expiratory volume in 1 sec (FEV1) of 1.2+/-0.4 l (range 0.58-1.86 l) were enrolled. Six patients were excluded due to inability to achieve a maximal test. Lung function and self-assessed every-day activities using a oxygen-cost diagram were evaluated before entry of the study. A maximal effort ramp-pattern cardiopulmonary exercise test (CPET) and a 6 MWT were conducted in random order. Borg score, heart rate, and O2 saturation with pulse oximetry (SpO2) were measured during both exercise tests. VO2 AT and minute ventilation were also measured during the CPET. Correlations were sought between the distance covered in the 6 MWT, and the D x W product with AT, VO2max and other variables. The average D and D x W were 456 m and 27.5 kg km(-1), respectively. D x W was superior to D alone when correlated with the VO2max and AT determined from the CPET, while modestly correlated with the change (delta) in Borg score and delta SpO2 in the 6 MWT and self-assessed every-day activities. Distance x weight product was correlated with the AT and VO2max. In addition, D x W was better correlated with diffusing capacity for carbon monoxide and vital capacity than D alone. We conclude that D x W mimics the work of walking better than D and is suggested as a parameter for evaluation of patients' fitness if gas exchange measurements are not available.
- Subjects :
- Activities of Daily Living
Aged
Exercise Test methods
Forced Expiratory Volume physiology
Heart Rate physiology
Humans
Male
Maximal Expiratory Flow-Volume Curves physiology
Middle Aged
Oximetry
Predictive Value of Tests
Residual Volume physiology
Total Lung Capacity physiology
Vital Capacity physiology
Anaerobic Threshold physiology
Body Weight physiology
Lung Diseases, Obstructive physiopathology
Oxygen Consumption physiology
Walking physiology
Subjects
Details
- Language :
- English
- ISSN :
- 0954-6111
- Volume :
- 95
- Issue :
- 7
- Database :
- MEDLINE
- Journal :
- Respiratory medicine
- Publication Type :
- Academic Journal
- Accession number :
- 11453321
- Full Text :
- https://doi.org/10.1053/rmed.2001.1115