Back to Search
Start Over
[Equine estrogens vs. esterified estrogens in the climacteric and menopause. The controversy arrives in Mexico].
- Source :
-
Gaceta medica de Mexico [Gac Med Mex] 2001 May-Jun; Vol. 137 (3), pp. 237-42. - Publication Year :
- 2001
-
Abstract
- It exists controversies about if the effects and benefits of the esterified estrogens could be similar to those informed for equines, because its chemical composition and bioavailability are different. Esterified estrogens has not delta 8,9 dehydroestrone, and its absorption and level of maximum plasmatic concentrations are reached very fast. In United States of America and another countries, esterified estrogens has been marketed and using for treatment of climacteric syndrome and prevention of postmenopausal osteoporosis, based on the pharmacopoiea of that country, but the Food and Drug administration (FDA) has not yet authorized up today, a generic version of conjugated estrogens. In Instituto Mexicano del Seguro Social (IMSS) and another institutions of health sector in Mexico, starting in year 2000, it has been used esterified estrogens for medical treatment of climacteric and menopausal conditions. For this reason, in this paper we revised the most recent information about pharmacology, chemical composition, clinical use and costs of the conjugated estrogens with the purpose to guide the decisions to purchase this kind of drugs in Mexican heath institutions.
- Subjects :
- Aged
Animals
Cost-Benefit Analysis
Drug Costs
Esterification
Estrogen Replacement Therapy economics
Estrogens chemistry
Estrogens economics
Estrogens isolation & purification
Estrogens, Conjugated (USP) chemistry
Estrogens, Conjugated (USP) economics
Estrogens, Conjugated (USP) isolation & purification
Female
Horses
Humans
Menopause
Mexico
Middle Aged
National Health Programs
Plants chemistry
Pregnancy
United States
United States Food and Drug Administration
Urine chemistry
Climacteric
Estrogen Replacement Therapy methods
Estrogens therapeutic use
Estrogens, Conjugated (USP) therapeutic use
Subjects
Details
- Language :
- Spanish; Castilian
- ISSN :
- 0016-3813
- Volume :
- 137
- Issue :
- 3
- Database :
- MEDLINE
- Journal :
- Gaceta medica de Mexico
- Publication Type :
- Academic Journal
- Accession number :
- 11432092