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[Dyshidrosis and acral purpura during polymorphic dermatitis in pregnancy: 2 cases].
- Source :
-
Annales de dermatologie et de venereologie [Ann Dermatol Venereol] 2001 Apr; Vol. 128 (4), pp. 531-3. - Publication Year :
- 2001
-
Abstract
- Background: We describe two severe cases of polymorphic eruption of pregnancy associated with dyshidrosis and purpuric lesions.<br />Case-Report: Two patients, primigravida at 35 and 34 weeks of amenorrhea, were admitted in our department for a severe and itchy eruption. In the first case, some papular lesions were particularly concentrated on the abdominal striae, associated with vesicles on the limbs. There were plantar dyshidrosis and purpuric macules on the toes. In the second case, there were a maculopapular eruption on the abdomen and limbs, some vesicles and bullae of palms and soles, and a purpura of heels. In both cases, the skin biopsy showed dermic inflammatory, direct immunofluorescence and Pemphigoide Gestationis Factor research were negatives. The two patients were treated with betamethasone dipropionate (Diprosone(R)), and hydroxyzine (Atarax(R)). They gave birth to healthy babies.<br />Discussion: Dyshidrosis is not exceptional in polymorphic eruption of pregnancy. Indeed, in the several series of polymorphic eruption of pregnancy we checked, a pompholyx distribution was observed in 5 p. 100 of the cases. It is not necessary a sign of pemphigoid gestationis, even if this localization is commonly observed. The purpuric lesions are unusual because, according to our knowledge, there is no description of purpura associated with palmoplantar lesions in polymorphic eruption of pregnancy. The purpuric lesions may be secondary to high capillary permeability, increased by severe dermic inflammation of the polymorphic eruption of pregnancy and, possibly, high level of circulating estrogens.
- Subjects :
- Administration, Topical
Adult
Anti-Inflammatory Agents therapeutic use
Antipruritics therapeutic use
Betamethasone therapeutic use
Biopsy
Drug Therapy, Combination
Eczema, Dyshidrotic drug therapy
Female
Glucocorticoids
Humans
Hydroxyzine therapeutic use
Parity
Pregnancy
Pregnancy Complications drug therapy
Pruritus drug therapy
Purpura drug therapy
Betamethasone analogs & derivatives
Eczema, Dyshidrotic complications
Eczema, Dyshidrotic pathology
Pregnancy Complications pathology
Pruritus complications
Pruritus pathology
Purpura complications
Purpura pathology
Subjects
Details
- Language :
- French
- ISSN :
- 0151-9638
- Volume :
- 128
- Issue :
- 4
- Database :
- MEDLINE
- Journal :
- Annales de dermatologie et de venereologie
- Publication Type :
- Academic Journal
- Accession number :
- 11395652