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The effects on platelet aggregation of oral prostaglandin E2 used for the induction of labour.
- Source :
-
British journal of obstetrics and gynaecology [Br J Obstet Gynaecol] 1975 Jun; Vol. 82 (6), pp. 449-52. - Publication Year :
- 1975
-
Abstract
- Secondary ADP induced platelet aggregation was inhibited in 17 patients after the administration of oral prostaglandin E2 tablets for the induction of labour. Primary ADP induced aggregation was shown to be inhibited by oral prostglandin E2 when the platelets responded to the lower concentration of 0-5 mug/ml of ADP. This inhibition was not detectable when the higher concentration of 1-0 mug/ml ADP was necessary. There would appear to be a decreased risk of thrombosis initiated by platelet aggregation as a result of using oral PGE2 tablets for inducing labour.
- Subjects :
- Adenosine Diphosphate antagonists & inhibitors
Adenosine Diphosphate pharmacology
Administration, Oral
Blood Cell Count
Depression, Chemical
Female
Humans
Pregnancy
Prostaglandins E administration & dosage
Thrombosis prevention & control
Labor, Induced
Platelet Adhesiveness drug effects
Platelet Aggregation drug effects
Prostaglandins E pharmacology
Subjects
Details
- Language :
- English
- ISSN :
- 0306-5456
- Volume :
- 82
- Issue :
- 6
- Database :
- MEDLINE
- Journal :
- British journal of obstetrics and gynaecology
- Publication Type :
- Academic Journal
- Accession number :
- 1138835
- Full Text :
- https://doi.org/10.1111/j.1471-0528.1975.tb00668.x