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[Non-small cell lung cancer with liver metastasis responsive to gemcitabine--a case report].

Authors :
Sakurai T
Oura S
Yoshimasu T
Tanino H
Kokawa Y
Nakamura T
Matsuyama K
Naito Y
Source :
Gan to kagaku ryoho. Cancer & chemotherapy [Gan To Kagaku Ryoho] 2001 May; Vol. 28 (5), pp. 707-10.
Publication Year :
2001

Abstract

A 56-year-old male patient underwent a right upper lobectomy and lymph node dissection for non-small cell lung cancer in March 1994. Multiple lung metastases in the right lung were found 45 months after the operation, and chemotherapy with docetaxel was administered. A liver metastasis was detected 11 months later, and it was refractory to docetaxel. Therefore, the patient was treated with cisplatin, mitomycin C and vinorelbine, which resulted in no change to the liver metastasis. He was next treated with gemcitabine, which resulted in a partial response of the liver metastasis. The adverse effects of gemcitabine were Grade 3 thrombocytopenia and Grade 2 neutropenia. The response duration for gemcitabine therapy was three months.

Details

Language :
Japanese
ISSN :
0385-0684
Volume :
28
Issue :
5
Database :
MEDLINE
Journal :
Gan to kagaku ryoho. Cancer & chemotherapy
Publication Type :
Academic Journal
Accession number :
11383223