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Ultrastructural characteristics of "aging" of human prostate cells in monolayer cell culture.

Authors :
RiemannJF
Brehmer B
Madsen PO
Bloodworth JM Jr
Source :
Urological research [Urol Res] 1975 May 30; Vol. 3 (1), pp. 13-20.
Publication Year :
1975

Abstract

Monolayer tissue culture cells from benign nodular hyperplasia of the prostate transferred at 1-2 weeks intervals were examined under the electron microscope after the 3rd, 9th, and 10th transfers. Changes seen after 9 to 10 transfers were interpreted as an "aging process" and consisted of the presence of lysosomes of various types and variations in the mitochondria profile. These changes were described in detail and illustrated and compared to the ultrastructural appearance of monolayer cell cultures in the early transfer stage.

Details

Language :
English
ISSN :
0300-5623
Volume :
3
Issue :
1
Database :
MEDLINE
Journal :
Urological research
Publication Type :
Academic Journal
Accession number :
1136078
Full Text :
https://doi.org/10.1007/BF00256191