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[Hydrodynamic efficiency of various forms of free DNA].

Authors :
Gannushkina IV
Antelava AL
Veĭko NN
Source :
Patologicheskaia fiziologiia i eksperimental'naia terapiia [Patol Fiziol Eksp Ter] 2000 Oct-Dec (4), pp. 3-5.
Publication Year :
2000

Abstract

DNA of blood plasma is the factor which corrects hydrodynamic resistance (HR) of blood flow and provides Thomes' effect. As comparative hydrodynamic effectiveness of various plasma DNA forms (nucleoprotein, thread and denaturated DNA isolated standardly from human leukocytes) remains unknown, the in vitro test identified HR of the flow of the above DNA forms weak solutions--10(-6) to 10(-5) g/ml--necessary for achievement of Thomes' effect in strictly similar hydrodynamic conditions warranting a turbulent flow (Re 8000). Thomes' effect was confirmed in blood samples in its absence in low-molecular solutions (glycerine) with the same asymptotic viscosity. It was found that HR of the flow of synthetic polymer solutions producing Thomes' effect depends on its initial concentrations. Hydrodynamic effectiveness in the used solutions of the nucleoprotein and DNA was high being comparable to that of the synthetic polymer widely used in production for obtaining Thomes' effect.

Details

Language :
Russian
ISSN :
0031-2991
Issue :
4
Database :
MEDLINE
Journal :
Patologicheskaia fiziologiia i eksperimental'naia terapiia
Publication Type :
Academic Journal
Accession number :
11247134