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Further insights into coronary debulking: the EUROCARE trial of directional atherectomy and the PACT trial of pullback atherectomy.
- Source :
-
Seminars in interventional cardiology : SIIC [Semin Interv Cardiol] 2000 Dec; Vol. 5 (4), pp. 185-92. - Publication Year :
- 2000
-
Abstract
- Although the principle of reducing plaque load in the coronary artery remains very appealing, clinical benefit from debulking devices has not been demonstrated unequivocally. Other approaches to prevent restenosis had been the application of various pharmacological agents. Unfortunately, the majority of clinical studies have not reproduced the promising results observed in the experimental laboratories. New frontiers in improving atherectomy devices and in optimizing concomitant medical treatment are currently being explored. We report on the EUROCARE trial investigating the possible benefit of carvedilol after coronary atherectomy, and the Pullback Atherectomy (PAC) pilot trial using a novel atherectomy device.<br /> (Copyright 2000 Harcourt Publishers Ltd.)
- Subjects :
- Carvedilol
Coronary Artery Disease drug therapy
Equipment Design
Humans
Randomized Controlled Trials as Topic
Adrenergic beta-Antagonists therapeutic use
Antioxidants therapeutic use
Atherectomy, Coronary instrumentation
Carbazoles therapeutic use
Coronary Artery Disease therapy
Propanolamines therapeutic use
Subjects
Details
- Language :
- English
- ISSN :
- 1084-2764
- Volume :
- 5
- Issue :
- 4
- Database :
- MEDLINE
- Journal :
- Seminars in interventional cardiology : SIIC
- Publication Type :
- Academic Journal
- Accession number :
- 11244515
- Full Text :
- https://doi.org/10.1053/siic.2000.0142