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Dopamine metabolism in the tuberculum olfactorium.

Authors :
Wilk S
Watson E
Glick SD
Source :
European journal of pharmacology [Eur J Pharmacol] 1975 Jan; Vol. 30 (1), pp. 117-20.
Publication Year :
1975

Abstract

The occurrence of the major dopamine metabolites, 3,4-dihydroxyphenylacetic acid (DOPAC) and homovanillic acid (HVA) in the tuberculum olfactorium of the rat was demonstrated by gas chromatography. The ratio of DOPAC to HVA in the tuberculum olfactorium was greater than the ratio of these metabolites in the striatum. The effect of pargyline and probenecid on dopamine metabolite levels was similar for both the tuberculum olfactorium and striatum.

Subjects

Subjects :
Animals
Chromatography, Gas
Corpus Striatum metabolism
Homovanillic Acid metabolism
Pargyline pharmacology
Phenylacetates metabolism
Probenecid pharmacology
Rats
Dopamine metabolism
Olfactory Bulb metabolism

Details

Language :
English
ISSN :
0014-2999
Volume :
30
Issue :
1
Database :
MEDLINE
Journal :
European journal of pharmacology
Publication Type :
Academic Journal
Accession number :
1122932
Full Text :
https://doi.org/10.1016/0014-2999(75)90212-5
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