Back to Search
Start Over
Synthesis of a conformationally restricted substrate analogue of siderophore biosynthetases.
- Source :
-
Organic letters [Org Lett] 2001 Feb 22; Vol. 3 (4), pp. 519-21. - Publication Year :
- 2001
-
Abstract
- [reaction: see text] A conformationally restricted analogue (5) of N(omega)-acetyl-N(omega)-hydroxyornithine and -lysine was synthesized. The synthesis features an efficient acylnitroso hetero-Diels-Alder cycloadduct (1) ring opening with palladium(0) and methylnitroacetate.
- Subjects :
- Catalysis
Lysine analogs & derivatives
Lysine chemistry
Molecular Structure
Ornithine analogs & derivatives
Ornithine chemistry
Palladium chemistry
Structure-Activity Relationship
Substrate Specificity
Lysine chemical synthesis
Ornithine chemical synthesis
Oxo-Acid-Lyases metabolism
Siderophores metabolism
Subjects
Details
- Language :
- English
- ISSN :
- 1523-7060
- Volume :
- 3
- Issue :
- 4
- Database :
- MEDLINE
- Journal :
- Organic letters
- Publication Type :
- Academic Journal
- Accession number :
- 11178814
- Full Text :
- https://doi.org/10.1021/ol006813+