Mechanistic Studies of Periodinane-Mediated Reactions of Anilides and Related Systems Professors M. G. Finn, A. Eschenmoser, and M. E. Newcomb are gratefully acknowledged for valuable discussions and suggestions. We thank Dr. D. H. Huang and Dr. G. Siuzdak for NMR spectroscopic and mass spectrometric assistance, respectively. We would also like to thank Dr. G. Vasilikogiannakis for helpful discussions and an anonymous referee for critical suggestions. Financial support for this work was provided by The Skaggs Institute for Chemical Biology, the National Institutes of Health (USA), a predoctoral fellowship from the National Science Foundation (P.B.), postdoctoral fellowships from ArrayBiopharma (N.Z.) and Bayer AG (R.K.), and grants from Abbott, Amgen, ArrayBiopharma, Boehringer-Ingelheim, Glaxo, Hoffmann-LaRoche, DuPont, Merck, Novartis, Pfizer, and Schering Plough.