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The role of plasma volume in the increase of aldosterone secretion rate during sodium deprivation.
- Source :
-
Clinical science and molecular medicine [Clin Sci Mol Med] 1975 Mar; Vol. 48 (3), pp. 161-5. - Publication Year :
- 1975
-
Abstract
- 1. 24 h aldosterone secretion rates (ASR) have been measured in six normal volunteers while recumbent all day and while standing for 12 h, on 200 and 10 mmol/day sodium diets and after salt-poor albumin infusions (75 g in 150 ml), which significantly expanded plasma volume. 2. The mean ASR on the 10 mmol/day sodium diet, both without and with the salt-poor albumin infusion, was highly significantly increased above the mean ASR on the 200 mmol/day sodium diet, both in the recumbent and in the upright posture. 3. There was no significant difference between the mean ASR values on the 10 mmol/day sodium diet alone and after the infusion of albumin either in the recumbent or in the upright posture. 4. The above abservations su;gest that sodium deprivation raises ASR by a mechanism or mechanisms unrelated to plasma volume.
Details
- Language :
- English
- ISSN :
- 0301-0538
- Volume :
- 48
- Issue :
- 3
- Database :
- MEDLINE
- Journal :
- Clinical science and molecular medicine
- Publication Type :
- Academic Journal
- Accession number :
- 1116336
- Full Text :
- https://doi.org/10.1042/cs0480161