Back to Search
Start Over
Obsessive-complusive disorder: pharmacological treatment.
- Source :
-
European child & adolescent psychiatry [Eur Child Adolesc Psychiatry] 2000; Vol. 9 Suppl 1, pp. I76-84. - Publication Year :
- 2000
-
Abstract
- Obsessive-compulsive disorder (OCD) in children and adolescents is often a disabling condition, which demands treatment with medication. Research shows that serotonin is involved in the disorder and empirical treatment studies show that antidepressants with serotonin activity are effective. The first choice of treatment in the psychopharmacological approach to OCD in children and adolescents are the SSRI agents, which have been documented as being effective as well as well-tolerated in children and adolescents. The best-documented SSRI to this point is sertraline. However, fluoxetine and fluoxamine have also undergone systematic studies in children and adolescents. Clomipramine has been proven effective, however, side effects caused by this agent would suggest that an SSRI is a better choice. Treatment with an SSRI seems to have effect in approximately 75 % of patients with OCD. There are still no systematic studies analyzing augmenting medication for children and adolescents with OCD. Research indicates that the combination of medication and psychotherapy (cognitive behavioural therapy) is important in most cases. Based on a few long-term follow-up studies on OCD children and adolescents there is not evidence that all children and adolescents suffer a lifetime course of the disease. It is therefore recommended that discontinuation is attempted after 1-1.5 years of successful treatment.
- Subjects :
- Adolescent
Child
Child, Preschool
Clinical Trials as Topic
Combined Modality Therapy
Female
Humans
Male
Obsessive-Compulsive Disorder psychology
Prognosis
Treatment Outcome
Cognitive Behavioral Therapy
Obsessive-Compulsive Disorder drug therapy
Selective Serotonin Reuptake Inhibitors therapeutic use
Subjects
Details
- Language :
- English
- ISSN :
- 1018-8827
- Volume :
- 9 Suppl 1
- Database :
- MEDLINE
- Journal :
- European child & adolescent psychiatry
- Publication Type :
- Academic Journal
- Accession number :
- 11140782
- Full Text :
- https://doi.org/10.1007/s007870070021