Back to Search Start Over

Accumulation of exogenous histone in rat brain parenchyma.

Authors :
Gorukhina OA
Ilyuk RD
Mishchenko IV
Source :
Bulletin of experimental biology and medicine [Bull Exp Biol Med] 2000 Jul; Vol. 130 (7), pp. 665-8.
Publication Year :
2000

Abstract

In vivo histoautoradiographic study of cerebral accumulation of exogenous histone after its intracarotid infusion to anesthetized rats with intact liver and animals with experimental cirrhosis showed that histone penetrates brain capillary endotheliocyte membranes and gets into the nervous tissue.

Subjects

Subjects :
Animals
Autoradiography
Blood-Brain Barrier
Histones administration & dosage
Liver metabolism
Liver physiology
Liver Cirrhosis, Experimental metabolism
Liver Cirrhosis, Experimental physiopathology
Rats
Brain metabolism
Histones metabolism

Details

Language :
English
ISSN :
0007-4888
Volume :
130
Issue :
7
Database :
MEDLINE
Journal :
Bulletin of experimental biology and medicine
Publication Type :
Academic Journal
Accession number :
11140581
Full Text :
https://doi.org/10.1007/BF02682100
Full Text Access
View/download PDF

Tools

Authors Abstract Subjects Details