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Oxidosqualene Cyclase Residues that Promote Formation of Cycloartenol, Lanosterol, and Parkeol We are grateful to Bridget M. Joubert for advice regarding mutagenesis. We thank Elizabeth A. Hart for an authentic parkeol standard, and for chromatographic and spectroscopic information. This research was funded by the National Institutes of Health (grant no. AI 41598) and the Robert A. Welch Foundation (grant no. C-1323). M.M.M. was an American Society of Pharmacognosy Undergraduate Fellow. M.J.R.S. was a Robert A. Welch Fellow and was supported by an NIH Biotechnology Training Grant (grant no. T32 GM08362).

Authors :
Meyer MM
Segura MJ
Wilson WK
Matsuda SP
Source :
Angewandte Chemie (International ed. in English) [Angew Chem Int Ed Engl] 2000 Nov 17; Vol. 39 (22), pp. 4090-4092.
Publication Year :
2000

Details

Language :
English
ISSN :
1521-3773
Volume :
39
Issue :
22
Database :
MEDLINE
Journal :
Angewandte Chemie (International ed. in English)
Publication Type :
Academic Journal
Accession number :
11093215
Full Text :
https://doi.org/10.1002/1521-3773(20001117)39:22<4090::aid-anie4090>3.0.co;2-8