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Total synthesis of a demethoxy-egonol from Styrax obassia.
- Source :
-
Archives of pharmacal research [Arch Pharm Res] 2000 Oct; Vol. 23 (5), pp. 438-40. - Publication Year :
- 2000
-
Abstract
- The total synthesis of a demethoxy-egonol isolated from Styrax obassia, 5-(3-hydroxypropyl)-2-(3',4'-methylenedioxyphenyl)benzofuran (9), is described. The key steps involve the construction of a 2-arylbenzofuran skeleton 7 from methyl 3-(4-hydroxyphenyl)propionate with 2-chloro-2-methylthio-(3',4'-methylenedioxy)acetophenone (6) in the presence of ZnCl2 and successive desulfurization of the resulting product 7.
- Subjects :
- Benzofurans chemical synthesis
Plants, Medicinal
Subjects
Details
- Language :
- English
- ISSN :
- 0253-6269
- Volume :
- 23
- Issue :
- 5
- Database :
- MEDLINE
- Journal :
- Archives of pharmacal research
- Publication Type :
- Academic Journal
- Accession number :
- 11059818
- Full Text :
- https://doi.org/10.1007/BF02976567