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Invasive bacterial infections of children in a rural province in the central Philippines.
- Source :
-
The American journal of tropical medicine and hygiene [Am J Trop Med Hyg] 2000 Mar; Vol. 62 (3), pp. 341-6. - Publication Year :
- 2000
-
Abstract
- The etiology of invasive bacterial infections was studied among 956 Filipino children less than five years old who fulfilled the World Health Organization criteria for severe or very severe pneumonia or had suspected meningitis or sepsis. The most common invasive infections were due to Streptococcus pneumoniae (12 [1.3%]) and Haemophilus influenzae (12 [1.3%]); including four cases of pneumococcal meningitis and 11 cases of H. influenzae meningitis. Type 1 was the most common (six of the 12 isolates) of the pneumococcal serotypes. Serotypes/groups 1, 6, 14, and 23 accounted for 91.7% of the invasive isolates. The majority of the H. influenzae strains from blood (10 out of 10) and cerebrospinal fluid (6 out of 7) were type b. Almost all of the invasive S. pneumoniae (9 out of 12) and H. influenzae (11 out of 12) infections were seen before one year of age, which stresses the need to investigate early immunization of children for H. influenzae type b and S. pneumoniae, as well as maternal immunization to maximize the potential of immunoprophylaxis.
- Subjects :
- Bacterial Infections prevention & control
Cerebrospinal Fluid microbiology
Child
Child, Preschool
Haemophilus influenzae classification
Haemophilus influenzae drug effects
Humans
Infant
Microbial Sensitivity Tests
Nasal Mucosa microbiology
Rural Health
Serotyping
Streptococcus pneumoniae classification
Streptococcus pneumoniae drug effects
Bacterial Infections etiology
Haemophilus influenzae isolation & purification
Streptococcus pneumoniae isolation & purification
Subjects
Details
- Language :
- English
- ISSN :
- 0002-9637
- Volume :
- 62
- Issue :
- 3
- Database :
- MEDLINE
- Journal :
- The American journal of tropical medicine and hygiene
- Publication Type :
- Academic Journal
- Accession number :
- 11037775
- Full Text :
- https://doi.org/10.4269/ajtmh.2000.62.341