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Recent advances in gestational trophoblastic disease.

Authors :
Schorge JO
Goldstein DP
Bernstein MR
Berkowitz RS
Source :
The Journal of reproductive medicine [J Reprod Med] 2000 Sep; Vol. 45 (9), pp. 692-700.
Publication Year :
2000

Abstract

Recent advances have increased our understanding of gestational trophoblastic disease, and epidemiologic studies have demonstrated that there are important differences in risk factors for complete and partial mole. Complete moles are now increasingly being diagnosed in the first trimester, affecting their clinical presentation and pathologic characteristics. While important advances have been made in chemotherapy, it is now recognized that etoposide is associated with a risk of second tumors. Several studies have advanced understanding of the molecular biology of gestational trophoblastic disease, and this is important for the eventual development of new and innovative therapy.

Details

Language :
English
ISSN :
0024-7758
Volume :
45
Issue :
9
Database :
MEDLINE
Journal :
The Journal of reproductive medicine
Publication Type :
Academic Journal
Accession number :
11027078