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Recent advances in gestational trophoblastic disease.
- Source :
-
The Journal of reproductive medicine [J Reprod Med] 2000 Sep; Vol. 45 (9), pp. 692-700. - Publication Year :
- 2000
-
Abstract
- Recent advances have increased our understanding of gestational trophoblastic disease, and epidemiologic studies have demonstrated that there are important differences in risk factors for complete and partial mole. Complete moles are now increasingly being diagnosed in the first trimester, affecting their clinical presentation and pathologic characteristics. While important advances have been made in chemotherapy, it is now recognized that etoposide is associated with a risk of second tumors. Several studies have advanced understanding of the molecular biology of gestational trophoblastic disease, and this is important for the eventual development of new and innovative therapy.
- Subjects :
- Antineoplastic Agents adverse effects
Antineoplastic Agents therapeutic use
Chorionic Gonadotropin, beta Subunit, Human blood
Etoposide adverse effects
Etoposide therapeutic use
Female
Humans
Incidence
Pregnancy
Prognosis
Risk Factors
Trophoblastic Neoplasms drug therapy
Trophoblastic Neoplasms genetics
Uterine Neoplasms drug therapy
Uterine Neoplasms genetics
Trophoblastic Neoplasms physiopathology
Uterine Neoplasms physiopathology
Subjects
Details
- Language :
- English
- ISSN :
- 0024-7758
- Volume :
- 45
- Issue :
- 9
- Database :
- MEDLINE
- Journal :
- The Journal of reproductive medicine
- Publication Type :
- Academic Journal
- Accession number :
- 11027078