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Oral benzquinamide in the treatment of nausea and vomiting.
- Source :
-
Clinical pharmacology and therapeutics [Clin Pharmacol Ther] 1975 Nov; Vol. 18 (5 Pt 1), pp. 554-7. - Publication Year :
- 1975
-
Abstract
- The clinical antiemetic effect of bezquinamide by oral route at a dosage of 100 mg 3 times daily was evaluated by a controlled double-blind method in 183 studies of patients treated with 5-fluorouracil. The incidence of nausea and vomiting in benzquinamide-treated patients was equal to that in placebo-treated patients and significantly higher than that in patients treated with prochlorperazine, 10 mg 3 times daily. Sedation was the only significant side effect observed, and this occurred at essentially equal rates in benzquinamide- and prochlorperazine-treated patients.
Details
- Language :
- English
- ISSN :
- 0009-9236
- Volume :
- 18
- Issue :
- 5 Pt 1
- Database :
- MEDLINE
- Journal :
- Clinical pharmacology and therapeutics
- Publication Type :
- Academic Journal
- Accession number :
- 1102233
- Full Text :
- https://doi.org/10.1002/cpt1975185part1554