Characterization of fluoroquinolone resistance among veterinary isolates of avian Escherichia coli.

Authors :: White DG
Piddock LJ
Maurer JJ
Zhao S
Ricci V
Thayer SG
Source :: Antimicrobial agents and chemotherapy [Antimicrob Agents Chemother] 2000 Oct; Vol. 44 (10), pp. 2897-9.
Publication Year :: 2000
Abstract: Fluoroquinolone-resistant avian Escherichia coli isolates from northern Georgia were investigated for gyrA and parC mutations. All isolates contained a mutation in GyrA replacing Ser83 with Leu; seven isolates also contained mutations replacing Asp87 with either Gly or Tyr. Random amplified polymorphic DNA analysis revealed that quinolone-resistant E. coli isolates were genetically diverse.

Subjects :: Animals
DNA Gyrase
DNA Topoisomerase IV
DNA Topoisomerases, Type II genetics
DNA, Bacterial drug effects
Escherichia coli genetics
Escherichia coli Infections epidemiology
Fluoroquinolones
Georgia epidemiology
Nalidixic Acid pharmacology
Polymorphism, Restriction Fragment Length
Reverse Transcriptase Polymerase Chain Reaction
Anti-Infective Agents pharmacology
Escherichia coli drug effects
Escherichia coli Infections microbiology
Escherichia coli Infections veterinary
Poultry microbiology
Poultry Diseases microbiology

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