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Chlamydia pneumoniae-associated ADEM.
- Source :
-
European journal of neurology [Eur J Neurol] 2000 Jul; Vol. 7 (4), pp. 435-8. - Publication Year :
- 2000
-
Abstract
- Inflammatory demyelinating diseases are a common cause of neurologic disability in young adults, and usually the cause is unknown. We describe a case of acute disseminated encephalomyelitis (ADEM) associated with Chlamydia pneumoniae infection. An 18-year-old previously healthy women, with a one-week history of coryzal illness, was admitted because of progressive headache, dizziness, and a left-sided hemiparesis. MR imaging of the brain and brainstem showed typical signs of ADEM. The diagnosis was established by PCR Chlamydia pneumoniae DNA positivity in a tracheal swab and by increasing titres of Chlamydia IgM antibody. The patient was treated with doxycycline and steroids and recovered completely. Apart from therapeutic implications, this case may contribute to our understanding of demyelinating diseases of the central nervous system.
- Subjects :
- Adolescent
Chlamydia Infections drug therapy
Encephalomyelitis, Acute Disseminated drug therapy
Female
Humans
Magnetic Resonance Imaging
Chlamydia Infections complications
Chlamydophila pneumoniae drug effects
Encephalomyelitis, Acute Disseminated microbiology
Encephalomyelitis, Acute Disseminated pathology
Subjects
Details
- Language :
- English
- ISSN :
- 1351-5101
- Volume :
- 7
- Issue :
- 4
- Database :
- MEDLINE
- Journal :
- European journal of neurology
- Publication Type :
- Academic Journal
- Accession number :
- 10971604
- Full Text :
- https://doi.org/10.1046/j.1468-1331.2000.00090.x