The rat vertex-middle latency auditory-evoked potential as indicator of anaesthetic depth: a comparison with evoked-reflex testing.

Authors :: Haberham ZL
van den Brom WE
Venker-van Haagen AJ
de Groot HN
Baumans V
Hellebrekers LJ
Source :: Brain research [Brain Res] 2000 Aug 11; Vol. 873 (2), pp. 287-90.
Publication Year :: 2000
Abstract: We investigated whether components from the rat Vx-MLAEP could be used to assess depth of anaesthesia induced by propofol. Propofol decreased MLAEP amplitudes and increased latencies. We propose that the P(16)-N(22) wave in the rat MLAEP is similar to the human P1, and that recovery of this wave during propofol anaesthesia correlates with behavioural measures of the regaining of consciousness.

Subjects :: Animals
Evoked Potentials, Auditory physiology
Female
Male
Propofol pharmacology
Rats
Rats, Wistar
Reflex physiology
Anesthesia methods
Evoked Potentials, Auditory drug effects
Reflex drug effects

Full Text Access

Tools