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Nosocomial transmission of echovirus 30: molecular evidence by phylogenetic analysis of the VP1 encoding sequence.
- Source :
-
Journal of clinical microbiology [J Clin Microbiol] 2000 Aug; Vol. 38 (8), pp. 2889-92. - Publication Year :
- 2000
-
Abstract
- We investigated six cases of enterovirus infection in a neonatal unit. The index patient, a 5-day-old boy, was admitted with aseptic meningitis due to echovirus 30 (E30). Secondary infections with E30 occurred in five babies. Comparison of the complete VP1 sequences showed that the isolates recovered from the index patient and his mother were closely related to those recovered from the five babies with secondary infections, demonstrating a nosocomial transmission of the virus. In the phylogenetic tree reconstructed from the VP1 sequences, the isolates formed a monophyletic cluster related to an E30 strain collected in June 1997 during an outbreak of aseptic meningitis.
- Subjects :
- Adult
Cross Infection epidemiology
Cross Infection virology
Disease Outbreaks
Echovirus Infections epidemiology
Echovirus Infections virology
Enterovirus B, Human isolation & purification
Feces virology
Female
Hospital Units
Humans
Infant, Newborn
Male
Meningitis, Viral epidemiology
Meningitis, Viral virology
Molecular Sequence Data
Phylogeny
Polymerase Chain Reaction methods
Capsid genetics
Cross Infection transmission
Echovirus Infections transmission
Enterovirus B, Human genetics
Meningitis, Viral transmission
Subjects
Details
- Language :
- English
- ISSN :
- 0095-1137
- Volume :
- 38
- Issue :
- 8
- Database :
- MEDLINE
- Journal :
- Journal of clinical microbiology
- Publication Type :
- Academic Journal
- Accession number :
- 10921945
- Full Text :
- https://doi.org/10.1128/JCM.38.8.2889-2892.2000