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Respiratory viral infections in adults with and without chronic obstructive pulmonary disease.
- Source :
-
American journal of respiratory and critical care medicine [Am J Respir Crit Care Med] 2000 Jul; Vol. 162 (1), pp. 167-73. - Publication Year :
- 2000
-
Abstract
- A longitudinal cohort study of older adults with chronic obstructive pulmonary disease (COPD) who were stratified by FEV(1) at enrollment was done to define the etiology, frequency, severity, and medical-care impact of respiratory tract viral infections (RTVIs). Controls consisted of a group of subjects of comparable age with the patients. RTVIs were documented in 44% of observed acute respiratory illnesses in control subjects and in 27% of COPD subjects, who were followed for mean periods of 35 and 26 mo, respectively. In this heavily influenza-vaccinated cohort ( approximately 90% vaccinated each year), picornaviruses, parainfluenza viruses, and coronaviruses were most commonly identified. Mean time to return to clinical baseline was approximately 2 wk in each group. Control and COPD subjects with mild airways obstruction (baseline FEV(1) >/= 50% predicted) had few emergency-center visits or hospitalizations. Approximately half of COPD subjects with moderate/severe COPD (baseline FEV(1) < 50% predicted) had at least one emergency-center visit and/or hospitalization for acute respiratory illness. RTVIs were documented in 23% of hospitalizations and in 45% of patients admitted between December and March. RTVIs have a major impact on utilization of health care resources for COPD patients with moderate/severe airways obstruction.
- Subjects :
- Aged
Female
Hospitalization statistics & numerical data
Humans
Influenza Vaccines
Longitudinal Studies
Male
Middle Aged
Respiratory Tract Diseases epidemiology
Respiratory Tract Diseases prevention & control
Time Factors
Virus Diseases epidemiology
Lung Diseases, Obstructive complications
Respiratory Tract Diseases complications
Respiratory Tract Diseases virology
Virus Diseases complications
Subjects
Details
- Language :
- English
- ISSN :
- 1073-449X
- Volume :
- 162
- Issue :
- 1
- Database :
- MEDLINE
- Journal :
- American journal of respiratory and critical care medicine
- Publication Type :
- Academic Journal
- Accession number :
- 10903237
- Full Text :
- https://doi.org/10.1164/ajrccm.162.1.9911019