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The presence of IgA on the surface of rat thoractic duct lymphocytes which contain internal IgA.

Authors :
Williams AF
Gowans JL
Source :
The Journal of experimental medicine [J Exp Med] 1975 Feb 01; Vol. 141 (2), pp. 335-45.
Publication Year :
1975

Abstract

The presence of lymphocytes with internal IgA among cells from rat thoracic duct lymph wdy. The number of cells detected was greater in animals kept in a convential animal house compared with those maintained under specific pathogen-free conditions. Thoracic duct lymph from B rats and adult thymectomized rats also contained cell with internal IgA. The surface Ig of the IgA-containing cells was studied using a double-labeling technique with (126I) anti-Ig to detect surface Ig, and fluorescein-conjugated anti-IgA in large amounts, but very little IgM and no surface IgG2. The surface IgA was not acquired passively.

Details

Language :
English
ISSN :
0022-1007
Volume :
141
Issue :
2
Database :
MEDLINE
Journal :
The Journal of experimental medicine
Publication Type :
Academic Journal
Accession number :
1089743
Full Text :
https://doi.org/10.1084/jem.141.2.335