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The presence of IgA on the surface of rat thoractic duct lymphocytes which contain internal IgA.
- Source :
-
The Journal of experimental medicine [J Exp Med] 1975 Feb 01; Vol. 141 (2), pp. 335-45. - Publication Year :
- 1975
-
Abstract
- The presence of lymphocytes with internal IgA among cells from rat thoracic duct lymph wdy. The number of cells detected was greater in animals kept in a convential animal house compared with those maintained under specific pathogen-free conditions. Thoracic duct lymph from B rats and adult thymectomized rats also contained cell with internal IgA. The surface Ig of the IgA-containing cells was studied using a double-labeling technique with (126I) anti-Ig to detect surface Ig, and fluorescein-conjugated anti-IgA in large amounts, but very little IgM and no surface IgG2. The surface IgA was not acquired passively.
- Subjects :
- Animals
Autoradiography
Female
Fluorescent Antibody Technique
Germ-Free Life
Immunoglobulin G analysis
Immunoglobulin M analysis
Iodine Radioisotopes
Male
Rabbits immunology
Rats
Rats, Inbred Strains
Thymectomy
Cell Membrane immunology
Immunoglobulin A analysis
Lymphocytes immunology
Thoracic Duct cytology
Subjects
Details
- Language :
- English
- ISSN :
- 0022-1007
- Volume :
- 141
- Issue :
- 2
- Database :
- MEDLINE
- Journal :
- The Journal of experimental medicine
- Publication Type :
- Academic Journal
- Accession number :
- 1089743
- Full Text :
- https://doi.org/10.1084/jem.141.2.335