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Synthesis, characterization and bioactivity of a new VO2+/aspirin complex.
- Source :
-
Journal of inorganic biochemistry [J Inorg Biochem] 2000 May 30; Vol. 80 (1-2), pp. 169-71. - Publication Year :
- 2000
-
Abstract
- A new VO2+ complex with salicylic acid acetate (Aspirin) of formula C18H18Cl2O12V2 was synthesized and characterized. Its biological effects upon cell proliferation, differentiation and promotion of tyrosine protein phosphorylation have been tested in two lines of osteoblast-like cells in culture.
- Subjects :
- Animals
Aspirin pharmacology
Blotting, Western
Bone and Bones metabolism
Cell Differentiation drug effects
Cell Division drug effects
Cells, Cultured
Humans
Osteoblasts drug effects
Phosphorylation
Phosphotyrosine metabolism
Spectrophotometry, Infrared
Vanadates pharmacology
Aspirin chemical synthesis
Vanadates chemical synthesis
Subjects
Details
- Language :
- English
- ISSN :
- 0162-0134
- Volume :
- 80
- Issue :
- 1-2
- Database :
- MEDLINE
- Journal :
- Journal of inorganic biochemistry
- Publication Type :
- Academic Journal
- Accession number :
- 10885481
- Full Text :
- https://doi.org/10.1016/s0162-0134(00)00026-x