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Cytotoxic cembrenolide diterpenes from the formosan soft coral lobophytum crassum.
- Source :
-
Journal of natural products [J Nat Prod] 2000 Jun; Vol. 63 (6), pp. 884-5. - Publication Year :
- 2000
-
Abstract
- A new cytotoxic cembrenolide diterpene, lobocrassolide (1), and a known cytotoxic cembrenolide, lobohedleolide (2), were isolated from the Formosan soft coral Lobophytum crassum. The structure of compound 1 was determined by 1D and 2D spectral analysis.
- Subjects :
- Animals
Bridged Bicyclo Compounds chemistry
Bridged Bicyclo Compounds pharmacology
Cytotoxins chemistry
Cytotoxins pharmacology
Diterpenes chemistry
Diterpenes pharmacology
Drug Screening Assays, Antitumor
Furans chemistry
Furans pharmacology
Humans
Leukemia P388 metabolism
Tumor Cells, Cultured drug effects
Bridged Bicyclo Compounds isolation & purification
Cnidaria chemistry
Cytotoxins isolation & purification
Diterpenes isolation & purification
Furans isolation & purification
Subjects
Details
- Language :
- English
- ISSN :
- 0163-3864
- Volume :
- 63
- Issue :
- 6
- Database :
- MEDLINE
- Journal :
- Journal of natural products
- Publication Type :
- Academic Journal
- Accession number :
- 10869230
- Full Text :
- https://doi.org/10.1021/np990620h