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7alpha-hydroxytheonellasterol, a cytotoxic 4-methylene sterol from the Philippines sponge Theonella swinhoei.
- Source :
-
Journal of natural products [J Nat Prod] 2000 Jun; Vol. 63 (6), pp. 841-2. - Publication Year :
- 2000
-
Abstract
- A new 4-methylene sterol, 7alpha-hydroxytheonellasterol (3), was isolated from the Philippines sponge Theonella swinhoei, along with the known compounds theonellasterol (1) and bistheonellide A. The structure of 3 was elucidated by interpretation of its spectroscopic data, which were compared with those of 1.
- Subjects :
- Animals
Antineoplastic Agents chemistry
Antineoplastic Agents pharmacology
Drug Screening Assays, Antitumor
Macrolides chemistry
Macrolides isolation & purification
Macrolides pharmacology
Magnetic Resonance Spectroscopy
Philippines
Spectrometry, Mass, Fast Atom Bombardment
Sterols chemistry
Sterols pharmacology
Tumor Cells, Cultured drug effects
Antineoplastic Agents isolation & purification
Porifera chemistry
Sterols isolation & purification
Subjects
Details
- Language :
- English
- ISSN :
- 0163-3864
- Volume :
- 63
- Issue :
- 6
- Database :
- MEDLINE
- Journal :
- Journal of natural products
- Publication Type :
- Academic Journal
- Accession number :
- 10869215
- Full Text :
- https://doi.org/10.1021/np9905665