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The basal SAR of a novel insulin receptor activator.
- Source :
-
Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2000 Jun 05; Vol. 10 (11), pp. 1189-92. - Publication Year :
- 2000
-
Abstract
- The synthesis and SAR of analogues prepared from novel insulin receptor activator 1 are described. Changes to the dihydroxyquinone core were not tolerated while functionalization of the two indoles contained in 1 resulted in little effect upon activation of the insulin receptor.
- Subjects :
- Structure-Activity Relationship
Receptor, Insulin agonists
Subjects
Details
- Language :
- English
- ISSN :
- 0960-894X
- Volume :
- 10
- Issue :
- 11
- Database :
- MEDLINE
- Journal :
- Bioorganic & medicinal chemistry letters
- Publication Type :
- Academic Journal
- Accession number :
- 10866378
- Full Text :
- https://doi.org/10.1016/s0960-894x(00)00206-7