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Obstructive pulmonary disease in rheumatoid arthritis.
- Source :
-
Arthritis and rheumatism [Arthritis Rheum] 1976 May-Jun; Vol. 19 (3), pp. 623-8. - Publication Year :
- 1976
-
Abstract
- Twenty-six of 43 patients (60.5%) with classic rheumatoid arthritis (RA) participating in a controlled, prospective study were found to have maximal midexpiratory flow rates (MMEFs) suggestive of obstructive pulmonary disease. Cigarette smokers with RA had significantly lower MMEFs than either nonsmokers with RA or smokers with degenerative joint disease. There was an increased prevalence of the Pi phenotype MS among the RA patients. Interstitial fibrosis, tobacco smoking, and protease inhibitor deficiencies were all significant factors in producing airway obstruction in patients with RA.
- Subjects :
- Adult
Aged
Arthritis, Rheumatoid genetics
Female
Humans
Lung Diseases, Obstructive diagnostic imaging
Lung Diseases, Obstructive genetics
Male
Middle Aged
Phenotype
Radiography
Respiratory Function Tests
Smoking complications
Ventilation-Perfusion Ratio
alpha 1-Antitrypsin analysis
Arthritis, Rheumatoid complications
Lung Diseases, Obstructive etiology
Subjects
Details
- Language :
- English
- ISSN :
- 0004-3591
- Volume :
- 19
- Issue :
- 3
- Database :
- MEDLINE
- Journal :
- Arthritis and rheumatism
- Publication Type :
- Academic Journal
- Accession number :
- 1084751
- Full Text :
- https://doi.org/10.1002/art.1780190316