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Obstructive pulmonary disease in rheumatoid arthritis.

Authors :
Collins RL
Turner RA
Johnson AM
Whitley NO
McLean RL
Source :
Arthritis and rheumatism [Arthritis Rheum] 1976 May-Jun; Vol. 19 (3), pp. 623-8.
Publication Year :
1976

Abstract

Twenty-six of 43 patients (60.5%) with classic rheumatoid arthritis (RA) participating in a controlled, prospective study were found to have maximal midexpiratory flow rates (MMEFs) suggestive of obstructive pulmonary disease. Cigarette smokers with RA had significantly lower MMEFs than either nonsmokers with RA or smokers with degenerative joint disease. There was an increased prevalence of the Pi phenotype MS among the RA patients. Interstitial fibrosis, tobacco smoking, and protease inhibitor deficiencies were all significant factors in producing airway obstruction in patients with RA.

Details

Language :
English
ISSN :
0004-3591
Volume :
19
Issue :
3
Database :
MEDLINE
Journal :
Arthritis and rheumatism
Publication Type :
Academic Journal
Accession number :
1084751
Full Text :
https://doi.org/10.1002/art.1780190316