[Orodental management in patients with malignant hematologic diseases who are waiting for bone marrow transplantation].

Background: This study aims to identify the main oral lesions caused by the use of chemotherapeutic agents pre- and post-transplant in malignant hemopathologies and to highlight the importance of dental prevention during this treatment in order to reduce and, if possible, avoid the resulting local and systemic complications.
Methods: Twenty-five patients were controlled, monitored and prepared to undergo the necessary chemo- and radiotherapy, as well as bone marrow transplantation in the majority of cases under the best possible oral conditions.
Results: The most commonly detected secondary lesions were reactions to cyclophosphamide and/or methotrexate. In general, this mucositis appeared 5-7 days after treatment and continued for 1-2 weeks before regressing without residue. Another post-radiotherapeutic complication observed was xerostomy.
Conclusions: Lastly, it is important to underline that patients receiving correct dental infection preventive treatment showed fewer tertiary lesions than those who did not undergo the same procedure.