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The potential role of the Arthus and Shwartzman reactions in the pathogenesis of pneumonic pasteurellosis.
- Source :
-
Inflammation research : official journal of the European Histamine Research Society ... [et al.] [Inflamm Res] 2000 Mar; Vol. 49 (3), pp. 98-101. - Publication Year :
- 2000
-
Abstract
- Pneumonic pasteurellosis (PP) is an economically important disease in cattle, sheep, and goats. Pasteurella haemolytica is commonly isolated from the severe fibrinopurulent pneumonia that characterize this respiratory syndrome. During infection, the bacteria produce leukotoxin (LKT) and lipopolysaccharide (LPS), both potent inducers of inflammation. Nonetheless, it has also been demonstrated that an exacerbated host's inflammatory response is responsible for the severe lung damage. Despite research in this field, the pathogenesis of PP is still incomplete. Two classical models of acute inflammatory response induced in laboratory animals, the Arthus and Shwartzman reactions, could explain the pathogenesis of the severe lung lesions that characterize PP.
- Subjects :
- Animals
Arthus Reaction etiology
Arthus Reaction immunology
Arthus Reaction pathology
Arthus Reaction veterinary
Pasteurellosis, Pneumonic etiology
Pasteurellosis, Pneumonic immunology
Pasteurellosis, Pneumonic pathology
Shwartzman Phenomenon etiology
Shwartzman Phenomenon immunology
Shwartzman Phenomenon pathology
Shwartzman Phenomenon veterinary
Subjects
Details
- Language :
- English
- ISSN :
- 1023-3830
- Volume :
- 49
- Issue :
- 3
- Database :
- MEDLINE
- Journal :
- Inflammation research : official journal of the European Histamine Research Society ... [et al.]
- Publication Type :
- Academic Journal
- Accession number :
- 10807496
- Full Text :
- https://doi.org/10.1007/s000110050565