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A simplified pharmacologic erection program for patients with spinal cord injury.
- Source :
-
The journal of spinal cord medicine [J Spinal Cord Med] 1999 Winter; Vol. 22 (4), pp. 303-7. - Publication Year :
- 1999
-
Abstract
- Introduction and Objectives: Intracavernosal injection (ICI) of vasoactive agents has been successfully used in the treatment of erectile dysfunction (ED). The authors' pharmacologic erection program, using a fixed combination of prostaglandin E1 (PGE1) and papaverine, is notable for its simplicity and acceptance by patients who have suffered spinal cord injuries (SCIs).<br />Methods: Patients undergo baseline questionnaire, physical examination, and hormone profile followed by instruction and injection of a fixed combination of PGE1 and papaverine. On successive visits, the patient injects himself and the dosage is titrated until a satisfactory erection is obtained. Patients who do not respond to injection of 1.0 cc are considered treatment failures. Patients return periodically for routine follow-up.<br />Results: From May 1994 to March 1997, 37 patients with SCI underwent initial evaluation and 28 (76%) responded to injection therapy and were successfully using self-injection therapy at 3-month follow-up. Twenty-three patients are still on injection therapy. Five patients have dropped out for several reasons including a lack of a current sexual partner (60%) and pain with injection (40%). Patient age ranges from 24 to 72. The dosage range was 0.10 to 0.50 cc (mean = 0.29 cc). The average duration of erection was 43 minutes. At 3-month follow-up, 85% of the patients rated their erections as good or excellent. Forty-three percent of patients are using ICI 1 or more times per week. Seventy-seven percent of patients are moderately or extremely satisfied with their treatment and 89% said that they would recommend this program to a friend.<br />Conclusions: This simplified pharmacologic erection program offers safe, well accepted, and effective therapy for ED to a SCI population with very high patient satisfaction.
- Subjects :
- Adult
Aged
Humans
Injections
Male
Middle Aged
Patient Satisfaction
Treatment Outcome
Alprostadil administration & dosage
Erectile Dysfunction rehabilitation
Papaverine administration & dosage
Penile Erection drug effects
Spinal Cord Injuries rehabilitation
Vasodilator Agents administration & dosage
Subjects
Details
- Language :
- English
- ISSN :
- 1079-0268
- Volume :
- 22
- Issue :
- 4
- Database :
- MEDLINE
- Journal :
- The journal of spinal cord medicine
- Publication Type :
- Academic Journal
- Accession number :
- 10751135
- Full Text :
- https://doi.org/10.1080/10790268.1999.11719584