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Collagen application for sealing of arterial puncture sites in comparison to pressure dressing: a randomized trial.
- Source :
-
The Journal of invasive cardiology [J Invasive Cardiol] 1999 Sep; Vol. 11 Suppl B, pp. 14B-18B. - Publication Year :
- 1999
-
Abstract
- Unlabelled: One-hundred patients undergoing routine diagnostic or interventional catheterization were randomly assigned to receive either percutaneously applied collagen (group A; n = 50) or conventional pressure dressing (group B; n = 50) for sealing of the femoral artery. Clinical variables were comparable in both groups. The heparin dose was 100 IU/kg in 30 patients and 200 IU/kg in 20 patients of either group. The average compression time was 4.3 minutes in group A and 42.3 minutes in group B (p < 0.001). Bleeding was not observed in group A but was observed in 6/50 patients in group B. The time to ambulation was 6.4 hours (range: 4-12 hours) in group A and 21.6 hours (range: 10-48 hours) in group B (p < 0.001). Hematomas with a diameter of > 6 cm developed in 4/50 patients in group A and in 11/50 patients in group B (p < 0.05). Blood transfusion or surgical interventions were not required and there was no loss of ankle pulses in either group.<br />Conclusion: Percutaneously applied collagen reduced compression time and duration of bedrest after diagnostic catheterization and PTCA. Despite earlier ambulation, the incidence of bleeding was lower with collagen than with conventional pressure dressing.
- Subjects :
- Aged
Bandages
Collagen therapeutic use
Equipment and Supplies
Female
Femoral Artery injuries
Hemostatics therapeutic use
Humans
Male
Middle Aged
Needlestick Injuries complications
Postoperative Hemorrhage etiology
Pressure
Treatment Outcome
Angioplasty, Balloon, Coronary adverse effects
Cardiac Catheterization adverse effects
Hemostatic Techniques
Needlestick Injuries therapy
Postoperative Hemorrhage prevention & control
Subjects
Details
- Language :
- English
- ISSN :
- 1042-3931
- Volume :
- 11 Suppl B
- Database :
- MEDLINE
- Journal :
- The Journal of invasive cardiology
- Publication Type :
- Academic Journal
- Accession number :
- 10745612