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Presence of cholinesterases in Echinococcus granulosus protoscolices.
Presence of cholinesterases in Echinococcus granulosus protoscolices.
- Source :
-
Parasite (Paris, France) [Parasite] 2000 Mar; Vol. 7 (1), pp. 47-50. - Publication Year :
- 2000
-
Abstract
- Cholinesterases were detected in protoscolices of Echinococcus granulosus spectrophotometrically and electrophoretically. To characterize these activities as acetylcholinesterases or pseudocholinesterases, BW284C51 and the organophosphate anthelmintic Neguvón were assayed as specific inhibitors of acetylcholinesterases, while Iso-OMPA was employed as specific inhibitor of pseudocholinesterases. We concluded that these cholinesterase (ChE) activities would be considered as possible targets in chemotherapy.
- Subjects :
- Acetylcholinesterase metabolism
Animals
Anthelmintics pharmacology
Benzenaminium, 4,4'-(3-oxo-1,5-pentanediyl)bis(N,N-dimethyl-N-2-propenyl-), Dibromide pharmacology
Cholinesterase Inhibitors pharmacology
Electrophoresis, Polyacrylamide Gel
Trichlorfon pharmacology
Cholinesterases metabolism
Echinococcus enzymology
Subjects
Details
- Language :
- English
- ISSN :
- 1252-607X
- Volume :
- 7
- Issue :
- 1
- Database :
- MEDLINE
- Journal :
- Parasite (Paris, France)
- Publication Type :
- Academic Journal
- Accession number :
- 10743648
- Full Text :
- https://doi.org/10.1051/parasite/2000071047