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Molecular and immunological analyses of the Borrelia turicatae Bdr protein family.

Authors :
Carlyon JA
Roberts DM
Theisen M
Sadler C
Marconi RT
Source :
Infection and immunity [Infect Immun] 2000 Apr; Vol. 68 (4), pp. 2369-73.
Publication Year :
2000

Abstract

Here, we describe the molecular and immunological characterization of the bdr gene family of Borrelia turicatae, a relapsing-fever spirochete. Nine bdr alleles belonging to two different subfamilies were sequenced and localized to linear plasmids. Anti-Bdr antiserum was generated and used to analyze Bdr expression in pre- and postinfection isogenic populations. The analyses presented here provide a detailed characterization of the Bdr proteins in a relapsing-fever spirochete species, enhancing our understanding of these proteins at the genus-wide level.

Details

Language :
English
ISSN :
0019-9567
Volume :
68
Issue :
4
Database :
MEDLINE
Journal :
Infection and immunity
Publication Type :
Academic Journal
Accession number :
10722647
Full Text :
https://doi.org/10.1128/IAI.68.4.2369-2373.2000