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Adamantylamide dipeptide stimulates hematopoiesis and increases survival in irradiated mice.

Authors :
Hofer M
Vacek A
Masek K
Juchelková L
Pipalová I
Source :
International journal of immunopharmacology [Int J Immunopharmacol] 2000 Jan; Vol. 22 (1), pp. 91-7.
Publication Year :
2000

Abstract

It has been demonstrated that the synthetic immunostimulatory compound, adamantylamide dipeptide (AdDP) produces hematopoiesis-stimulating effects in mice exposed to sublethal doses of ionizing radiation and increases survival in experimental animals irradiated with a lethal dose. These findings might suggest contingent extension of clinical indications for the administration of AdDP for the conditions of hematopoietic suppression, especially in oncology.

Details

Language :
English
ISSN :
0192-0561
Volume :
22
Issue :
1
Database :
MEDLINE
Journal :
International journal of immunopharmacology
Publication Type :
Academic Journal
Accession number :
10684992
Full Text :
https://doi.org/10.1016/s0192-0561(99)00072-7