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[Mutagenicity study of gadobenate dimeglumine formulation (E7155) (1)--Reverse mutation assays in S. typhimurium and E. coli tester strains].

Authors :
Hakura A
Sagami F
Tirone P
Morisetti A
Bussi S
Fassio F
Source :
The Journal of toxicological sciences [J Toxicol Sci] 1999 Nov; Vol. 24 Suppl 1, pp. 89-94.
Publication Year :
1999

Abstract

The ability of gadobenate dimeglumine formulation (E7155) to cause gene mutations was assessed in five strains of Salmonella typhimurium (TA100, TA1535, TA98, TA1538, and TA1537) and a strain of Escherichia coli (CM891; WP2, uvrA-, pKM101) using the Ames test (agar plate assay). The results suggest that E7155 is non-mutagenic towards these bacterial tester strains.

Details

Language :
Japanese
ISSN :
0388-1350
Volume :
24 Suppl 1
Database :
MEDLINE
Journal :
The Journal of toxicological sciences
Publication Type :
Academic Journal
Accession number :
10637783
Full Text :
https://doi.org/10.2131/jts.24.supplementi_89