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Evaluation of the accuracy of preoperative staging in thoracic esophageal cancer.
- Source :
-
The Annals of thoracic surgery [Ann Thorac Surg] 1999 Dec; Vol. 68 (6), pp. 2059-64. - Publication Year :
- 1999
-
Abstract
- Background: Exact clinical staging before treatment of esophageal cancer has become increasingly important in the evaluation and comparison of the results of different treatment modalities, including surgery, chemotherapy, and radiotherapy.<br />Methods: The accuracy of preoperative tumor staging by using an esophagography, esophagoscopy, percutaneous and endoscopic ultrasonography, and computed tomography was assessed in 224 patients with resectable esophageal cancer. The results of tumor staging by these tests were compared prospectively with the pathologic stage of the esophagectomy specimens with respect to the T and N categories defined by the International Union Against Cancer TNM classification.<br />Results: For the T category, the overall accuracy was 80%. For the N category, overall accuracy was 72%, with a sensitivity of 78%, a specificity of 60%, and a positive predictive value of 78%. Overall, the accuracy of stage grouping was 56%.<br />Conclusions: Either the T or N categories can be predicted reliably by clinical staging techniques. However, the preoperative stage grouping might not be valid in resectable, localized esophageal cancer.
- Subjects :
- Adult
Aged
Aged, 80 and over
Carcinoma, Squamous Cell diagnosis
Carcinoma, Squamous Cell pathology
Carcinoma, Squamous Cell surgery
Esophageal Neoplasms pathology
Esophageal Neoplasms surgery
Esophagectomy
Female
Humans
Lymphatic Metastasis
Male
Middle Aged
Neoplasm Staging
Predictive Value of Tests
Prospective Studies
Sensitivity and Specificity
Esophageal Neoplasms diagnosis
Subjects
Details
- Language :
- English
- ISSN :
- 0003-4975
- Volume :
- 68
- Issue :
- 6
- Database :
- MEDLINE
- Journal :
- The Annals of thoracic surgery
- Publication Type :
- Academic Journal
- Accession number :
- 10616977
- Full Text :
- https://doi.org/10.1016/s0003-4975(99)01171-6